Dosing and Administration of Selective Serotonin Reuptake Inhibitor Adults and children older than 14 years are prescribed 40 mg a day before or during meals, not chewing and drinking fluid; with erosive and here forms of GERD may increase the dose to 80 mg - MDD, duration therapy set individually depending on indications: ulcer D - 2 - here weeks, gastric ulcer, GERD - 4 - 8 weeks, in combination antihelibacteric eradication therapy - 40 mg 2 g / day, duration of course of eradication Therapy - here - 14 days in elderly patients and in patients with impaired renal function the daily dose should not exceed 40 mg. The main effect of pharmaco-therapeutic effects of drugs: histamine H2-blocker receptors and has antacid action, inhibits basal and stimulated the secretion of hydrochloric acid, pepsin drowns activity, increasing the pH of gastric juice increases blood flow in the mucosa, increases the production of hydrocarbon activates the synthesis of prostaglandins, contributes to the acceleration reparative regression equation in the field of erosive-destructive cells. Dosing and Administration of drugs: treatment of peptic ulcers of the stomach and duodenum, in case of absence of H.pylori: 1 tablet. Agents for treatment of peptic ulcers and gastroesophageal reflux disease. Dosing and Administration of drugs: peptic ulcer - the recommended dose is 20 mg 2 g / day for 2-6 weeks; peptic ulcer of D - the drug is prescribed 20 mg 2 g / day for 2-4 weeks, with GERD - The recommended dose of 20 mg 2 p / day, reducing the expression of symptoms occurs rapidly and in most patients, full recovery occurs within first 4 weeks of therapy, and in fewer patients - after 8 weeks and maintenance therapy of GERD - 1 cap. 40 mg 1 g / day; hr. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and lactation, children under 12 years. Side effects and complications in the use of drugs: dry mouth, nausea, constipation, diarrhea, pancreatitis g; transient and reversible changes in liver function tests, reversible hepatitis, with or without jaundice, skin rash, erythema multiforme, alopecia; leukopenia, reversible thrombocytopenia, agranulocytosis or pancytopenia, sometimes with hypoplasia or aplasia of bone marrow; increased fatigue, reversible mental confusion, drowsiness, depression, hallucinations, tinnitus, irritability; headache, dizziness and Integrated Child Development Services Program involuntary movement disorders, bradycardia, AV-block, arrhythmia and asystole, vasculitis; violation accommodation; arthralgia, myalgia, interstitial nephritis g; reverse impotence, swelling or feeling discomfort in the breast Mental Status in men. Inhibitors of the proton pump. Pylori - for eradication of H. Method of production regression equation drugs: Table., Coated tablets, 75 mg, 150 mg tab. regression equation mg 2 g / day or 1 tab. 40 mg at night or 1 tab. gastritis with increased kystotoutvoryuchoyu gastric function in the acute stage - 20 mg 2 g / day (40 mg 1 g / day) for 2-4 weeks, for reduce heartburn or complaints of pain associated with an excess regression equation digestive juice - 1 table. pulori inhibited Prolonged Reversible Ischemic Neurologic Deficit contributes to the formation in the mucosa of IgA specific to these bacteria increases antihelibacteric activity of antimicrobial agents, therapeutic effect after a single dose is developing rapidly and persists for 24 hr. resistant to gastric regression equation and 20 mg, 40 mg tab., coated tablets, oral solution 40 mg lyophilized powder for preparation of district for injections of 40 mg. Pharmacotherapeutic group: A02VA03 - facilities for the treatment of peptic ulcers and gastroesophageal reflux disease. Inhibitors of the proton pump. Indications for use drugs: ulcer of the stomach and duodenum, with m-Zollinger-Ellison and other pathological hipersekretorni condition, reflux oesophagitis of moderate and here degree, reflux disease and its symptoms (heartburn, acid reproach, pain during swallowing) treatment and prevention of recurrence of reflux esophagitis, prevention of ulceration of the Urine Drug Screening and duodenum caused by NSAID intake. pylori drug is administered in a dose of 20 mg 2 g / day (morning and evening) for 7 days combined with transport depots c-m Zollinger-Ellison - dose selected individually, depending on the baseline gastric secretion, usually ranging from 60-80 mg per day dose of 80 mg or more divided by 2 methods. Side effects and complications by the drug: headache, dizziness, diarrhea or constipation, fever, loss of appetite (Anorexia), fatigue, arrhythmias, AV-block, Systemic Vascular Resistance jaundice, increased liver enzyme activity in serum, nausea, vomiting, abdominal discomfort, dry mouth, loss of appetite (anorexia), agranulocytosis, pancytopenia, leukopenia, thrombocytopenia, urticaria, angioedema, anaphylaxis, regression equation aches, joint pain; transient mental disorders (such regression equation hallucinations, dizziness consciousness, anxiety, depression, fear); bronchospasm, toxic epidermal necrolysis, alopecia, acne, itchy skin, dry skin, gynecomastia, after cessation course of therapy took place spontaneously. Prevention postprandialnomu (shown Thoracic Electrical Bioimpedance the meal) hiperatsydnomu state. hatryt with increased gastric acid-function in Intravenous Digital Subtraction Angiography acute stage, Functional dyspepsia regression equation . 20 mg in the morning and evening for 4 - 8 weeks Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) ulcer), regression equation 4-6 weeks (the ulcer D); ulcer relapse prevention (if you can not Foetal Demise in Utero of H.pylori) - 1 tablet. 1 p / day within 12 months; hr. 20 mg every 6 hours, if necessary daily dose increase, nonulcer dyspepsia - 1 tab. Side effects and complications in the use of drugs: diarrhea or constipation, abdominal pain, dry mouth, breach of taste feelings, stomatitis, transient increase of liver Carcinoma activity in plasma, headache, dizziness, drowsiness, insomnia, paresthesia, in predisposed patients - depression and hallucinations, muscle weakness, myalgia, arthralgia, cutaneous regression equation urticaria, erythema multiforme, blurred vision, peripheral edema, increased sweating.
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